AFAO develops its program of work in accordance with priorities identified in Australia's Sixth National HIV Strategy.

The Sixth National HIV Strategy, launched in May 2010, clearly identifies priority action areas which include exploring options for more innovative prevention programs targeting gay men, as well as how best to address emerging issues such as the increasing rates of injecting among Aboriginal and Torres Strait islander communities. Complementing these actions targeting specific affected communities are over-arching Priority Areas for Action in respect of human rights, legislation and anti-discrimination.

These complementary and mutually reinforcing activities under the National HIV Strategy will ensure that due regard is had to human rights and discrimination issues faced by gay men, Aboriginal and Torres Strait Islanders and injecting drug users in the development and implementation of HIV prevention, care and support initiatives targeting these communities. These national strategies were developed with significant contributions from community stakeholders, research organisations, medical professionals and state and territory health departments.

The five strategies are:

The Sixth National HIV Strategy

The First National Hepatitis B Strategy

The Second National Sexually Transmissible Infections Strategy

The Third National Hepatitis C Virus (HCV) Strategy and

The Third National Aboriginal and Torres Strait Islander Blood Borne Viruses and Sexually Transmissible Infections Strategy